The Effect of Preoperative Intravenous Dexamethasone on Postoperative Pain after Surgery of Inguinal Hernia

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Kamran Hadavand Mirzaie Mehrdad Taghipour Mohammad Hossein Broujerdi Nourodin Mousavi Nasab Ali Habibi Mohammad Moslemi


Background: Postoperative pain is a problematic area in surgery as evidenced by frequent reports of therapies in the literature. Pain can lead to serious complications such as vomiting, aspiration, dehydration, electrolyte disturbances and disruption of incision site. In the present study, we examined whether pre-incisional intravenous dexamethasone provides less pain after surgery of inguinal hernia.

Method: Fifty-six patients, scheduled for surgery of inguinal hernia, were included and randomly assigned to the control and study groups. In the control group patients received only the anesthesia drugs whereas those in the study group received intravenous dexamethasone; 8 mg, and VAS questionnaire was completed 1,6,12,18,24,48 hours after the operation.

Results: In the present study, there were demographic data and differences among the two groups. In the study group patients who received dexamethasone; 8 mg, showed significant differences concerning post- operative pain.

Conclusion: We found that pre-incisional treatment with intravenous dexamethasone 8mg causes significant differences in post-operative pain between the two groups. However, with consideration of pain complications and the research which represents the drug efficacy in higher doses, conducting further studies and in other kinds of surgeries are recommended.

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